Wound Nail Dx Service
Rapid and accurate solution eliminates guess work in diagnosing and treating wound infections.
The complexity of the bacterial population present in diabetic foot ulcers is much greater than would be expected from culture studies alone. Patients with diabetes are believed to have a 12-25% lifetime risk of developing a foot ulcer.
Bacteria can exist within the wound as multi-layered microbial communities, known as biofilms, surrounded by self-produced protective extracellular slime'. More fastidious organisms may not be identified with standard culture, resulting in a delay in the appropriate treatment.
Molecular methods are advancing and becoming more accessible and affordable and it is now possible to use bacterial DNA from the wound site to identify the pathogens present. Wound Nail Dx quickly identifies pathogens and detects potential antibiotic resistance, so effective treatment can begin sooner.
Accurate diagnosis within 24 hours with real-time PCR for pathogen identification and detection of antibiotic resistance :
- PCR, a molecular technique, can be used to precisely analyze the genetic material of pathogens
- Provides a more definitive diagnosis than POC antigen assays
- 24-hour turnaround from receipt of specimen
- More accurate than conventional culture
Helps improve clinical confidence and decrease patient risks:
- Detects polymicrobial infections
- Unaffected by concurrent antibiotic use
- Identifies potential antibiotic resistance
- Aids in quick clinical decision-making
- Reduces false negative results
- Aids in antibiotic stewardship
- Reduces potential unnecessary drug exposure
Wound Dx Test Menu
- Klebsiella pneumoniae, oxytoca
- Pseudomonas aeruginosa
- Staphylococcus (epidermidis, haemolyticus, lugdunensis, saprophyticus)
- Staphylococcus aureus
- Staphylococcus enterotoxins A, B
- Stenotrophomonas maltophilia
- Streptococcus agalactiae (group B strep)
- Streptococcus pneumoniae
- Streptococcus pyogenes (group A strep)
- Vibrio cholerae, parahaemolyticus, vulniflcus
- Yersinia enterocolitica
Bacterium
- VanA, VanB (Vancomycin Resistance Genes)
- mecA (methicillin Resistance Genes)
- ermB, C; mefA (Macrolide Lincosamide Streptogramin Resistance)
- qnrA2 (Fluoroquinolone Resistance Genes)
- tet M (Tetracycline Resistance Genes)
- SHV, KPC Groups (Class A Beta Lactamase)
- CTX-M1 (15}, M2 (2), M9(9}, M8/25 Groups (Class A Beta Lactamase)
Antibiotic Resistance Test Menu
- Aspergillus flavus, fumigatus, niger, terreus Blastomyces dermatitidis
- Candida albicans, glabrata, parapsilosis, tropicalis
- Curvularia lunata
- Cladosporium herbarum Epidermophyton floccosum
- Fusarium oxysporum, solani
- Malassezia furfur, restricta, sympodialis, globose
- Microsporum audouinii, can is, gypseum Trichosporon mucoides, asahii Trichophtyton mentagraphophytes/ interdigitale, rubrum, soudanense, terrestre, tonsurans, verrucosum, violaceum
- IMP,NDM,VIM Groups (Class B Metallo Beta Lactamase)
- ACT, MIR, FOX, ACC Groups (AmpC Beta Lactamase)
- OXA-48,-51 ( Class D Oxacillinase)
- Per-1NEB-1/GES-1 Groups (Minor Extended Spectrum Beta Lactamase)
- Dfr (Al, AS}, sul (1, 2) Probes (Trimethoprim/Sulfamethoxazole Resistance)
Fungal
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